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lambdagrrl 1. I knew somebody who did this and damaged her liver because she was getting the dosages wrong.
2. There is a cis-lead science/art project working to do this with/for trans women. They're based in the US at a university. I can dig up their names if you're interested. It was started by a cis het man who wanted to brew birth control for his girlfriend, but then he was joined by a cis woman who thought it might be useful to teach trans women who to splice genes for oestrogen production. It's meant to be political, but I found it such an alarmingly american way to respond to the healthcare crisis (read: 'hacking!' rather than collective action) that I was kind of alarmed by the whole thing.