@kara @Leucrotta @green Acetaminophen alone can, in excess or with long term use, can cause liver failure.
What I've read about kava-kava is about 50/40/10: "this is dangerous"/"this could be dangerous"/"this stuff is safe".
So yeah, I personally stay away from kava-kava usually. Œstrogen can stress the liver, and I'm already taking it; no sense flirting with needing borrowed organs, IMO.