Maybe another day I'll tell you about a guilty pleasure of mine. I don't know how popular it is really :

Desert Punk. ( Sunabōzu )

It's western/sf too, a grim settings where you live using whatever aces you got, and sometimes it's not the physically strong that are the fittest.
What I find great about it is the protagonist is actually a terrible human being.
There is also a female character using her body as an ace and... it works rather great for her. Another is fighting for a cause, and another just want to be the best mercenary. More variety of female character than most show!

However be warned there are various trigger in this show. Notably rape.